Santoni, who was perhaps best known as the hygiene-averse pizza maker on the classic sitcom, also starred in "Dirty Harry."
His first acting role was in the 1970 film, "Hercules In New York."
The comedian perfectly summed up the answer to an often-asked question on Howard Stern's radio show.
Julia Louis-Dreyfus and Jason Alexander recently reminisced about Jerry Stiller.
"He will be greatly missed," his son, Ben Stiller, wrote on Twitter.
"I think you're a little confused, but it's a pleasure to be here," George Shapiro told the late night TV host.
The streaming giant has acquired the distribution rights to the beloved sitcom.
The presidential candidate had a "Seinfeld" moment in the middle of the debate.