We’re not entitled to know a single detail about a celebrity’s personal life ― much less their medical history. But stars who have chosen to come forward about their experiences with in vitro fertilization and gestational surrogacy are playing an enormous role in helping to destigmatize infertility, an often painful and stigmatized medical condition that affects almost one in six couples in the U.S.
Infertility is the inability to have a baby after 12 months of unprotected sex. Secondary infertility is the inability to have a child after having successfully given birth to a first. The causes of either condition are diverse and complex, and IVF, which is when doctors extract mature eggs from the mother and fertilize them with sperm from the father in a lab, is the most effective way to treat infertility. If any eggs are fertilized successfully, they can be placed back inside the uterus to give it a chance to implant and become a pregnancy.
Success rates can vary depending on things like the age of both parents and other pre-existing medical conditions. Currently, about 1.6 percent of all babies born in the U.S. were conceived with assisted reproductive technology, and the U.S. Centers for Disease Control and Prevention note that the rate of ART procedures are probably smaller compared to the potential demand for these techniques. Cost is one big barrier keeping couples from IVF; one single IVF cycle costs an average of $12,400 in the U.S., according to the American Society for Reproductive Medicine, and the procedures are rarely covered by health insurance.
The people in the story below all have different reasons for arriving at the decision to attempt IVF. The thing that unites them all, in addition to grief over miscarriages and failed IVF attempts, is their hope to complete their families on their own terms. Read on and be inspired.

But a lot can happen in three years, and now that she and Odom are separated, Kardashian is glad that the fertility treatments did not work, she said in a March 2016 episode of "Kocktails with Khloe."
“At the time, I was like ugh! Gotta have a baby. That’s all I wanted at that time. And I thought maybe it would like, fix the situation. So I’m also happy that it didn’t happen. I was young, I was 27, and I thought, Oh my god, a baby will fix this!" Kardashian went on to say that she hopes that she has children one day.

Teigen took the criticism in stride, saying on Twitter that misunderstanding about the IVF process in general may have led some to believe that the couple had done IVF specifically to make a female embryo, or that “choosing” a female embryo meant discarding all the male embryos. In fact, that’s far from the case, and Teigen said that she and her husband have several embryos of both sexes in storage for future children. The controversy didn’t stop her from making a joke about it, though.
"I also picked the embryo with a taste for bacon, a knack for magic and size 7 feet so she can always find shoes."

"While you're going through IVF and get pregnant, every day [the feeling is], We're still holding! We're still holding…!” Jackman said. "You know how precarious it is and how much she's been through to get there. And [miscarriage] is a massive letdown. It's really difficult -- and much harder for the woman."
The couple then began exploring adoption in the U.S., because Australia, where they’re from, didn’t allow couples to pursue both adoption and IVF at the same time. Eventually the couple ended up adopting two children: a newborn boy in 2000 and a newborn girl in 2005.

"It was a sad process for me to become a mom, and a long process,” Vardalos said to People. "I felt so embarrassed that I couldn't have a biological child.”
But she eventually did become a mom. In 2008, the California foster care system matched the couple with a three-year-old girl who would eventually become their daughter. Vardalos wrote about her experience in the book Instant Mom, which came out in 2013, and she is now an outspoken advocate for adoption.

"It helped that other moms had said that once they had their babies, they forgot they were ever pregnant,” she told them in a 2012 interview. "So once my focus became the baby and not the pregnancy, it was a very easy decision.”

"My first IVF I did get pregnant -- that was the miscarriage," Rancic said. "But the second one, I did not get pregnant, and that was the biggest kick in the stomach, because I just could not believe you go through so much to get those eggs and put them in, and when the doctor calls you, to hear, 'Oh, sorry, it didn't work.' That was the most shocking. I would go, 'I'm a good person, and I could give someone the greatest life of all, but yet I can't get pregnant.'"

"I remember one time I just had a miscarriage and Rachel was giving birth,” Cox said in a 2004 interview with Dateline NBC, the year “Friends” ended. "It was like that same time. Oh my God, it was terrible having to be funny."

"I had tried and failed and failed and failed,” Kidman said in a 2008 interview with Australia’s Who magazine. "Not to be too detailed, but I’ve had an ectopic pregnancy, miscarriages and I’ve had fertility treatments. I’ve done all the stuff you can possibly do to try get pregnant. Every woman who has been through all those ups and downs knows the depression that comes with it. So the way it just happened with Sunday was like, ‘What?’ The percentages were so low. It is the miracle in my life.”

"Meeting your children rather than giving birth to them, it’s as if, um, it’s -- suspended animation,” she said to Vogue. "The gestational experience is gone. It’s as if everything else disappears for a moment, and the world goes silent and -- I can’t explain it except to say that nothing else existed.”

"The whole process was quite an ordeal, and we became slaves to the time of day and to little vials of liquid," Shields wrote. "We'd find ourselves out at dinner with friends, and then we'd have to sneak off to a coat room, where we'd huddle over syringes and a travel-size cooler filled with small bottles of drugs."
She ended up conceiving again, this time without assistance, and gave birth to her second daughter in 2006.

"IVF is very upsetting. It's a brutal process and it's very emotional. It's really hard,” said Wise in a 2014 interview with The Daily Mail. "But then you pick yourself up, look around and see this unbelievably beautiful little baby you've got anyway."
The couple eventually went on to adopt 16-year-old son Tindyebwa Agaba, a former Rwandan child soldier who had moved to Britain.

She told the Daily Mail back in 2013 that every time an IVF attempt failed, it was a disappointment not only to herself and her husband, but their oldest child.
"‘I needed to protect myself a little by thinking that I already had one child,” she told the Daily Mail. "I couldn’t make all my life, my spirituality, my strength, my happiness, dependent on the next pregnancy. I would say to René-Charles, “I hope you are going to have a brother or sister,” and each time when it didn’t work I’d tell him, “It didn’t work, we’ll try again.”