"The whole world celebrated our moon landing, but we missed the whole thing because we were out of town," Aldrin jokes in the video. "So now I invite you to share with me and the world, your story or your family's story of where you were on July 20th, 1969."
On that historic day, Neil Armstrong took the first step onto the lunar surface at 22:56:15 EDT. Aldrin joined him about 20 minutes later.
Celebrities are already buzzing about the anniversary, from Bill Nye to Stephen Colbert to John Travolta.
"I was five years old and my mom swears she got me up and she put me in front of the TV with my other ten brothers and sisters," Colbert says in the video.
"We were jumping in and out of the pool, getting updates every three to five minutes," Travolta says. "Did something happen? How close are they? Did they walk yet?"
You can share your memories of the historic event on social media using the hashtag #Apollo45. The Youtube Page "Apollo 45" will feature videos about the moon landing posted by users around the world.
Twitter users have already started sharing their stories.
How about you? Join the conversation!