One photographer who is popular on the service reacted to the news with three words: "Instagram's suicide note." No hashtags needed.
Phrases like "deleting Instagram," "killing Instagram," "goodbye Instagram" and countless others with similar expressions are spreading on Twitter by the minute.
Among the changes: Instagram has the right to sell your photos (update: Instagram says it has no "intention" to do so), CNET reports. Your data, including meta-data like your geo-location, can also be used for ad targeting, and ads won't necessarily be clearly marked, the new Terms of Service say.
What can you do? As The Verge says, "users will look elsewhere," and there are a number of options. Have a look at some of them below.
Jason Gilbert contributed to this slideshow. An earlier version of it appeared here.