Biden's latest comment came during a visit to Wisconsin where he was campaigning for Democratic Sen. Russ Feingold. When the vice president stopped at Kopp's Frozen Custard for an icy treat, the shop's manager casually suggested to the veep that the Obama administration "lower our taxes." Biden's response: "Why don't you say something nice instead of being a smartass all the time?"
The vice president's remark was made in jest at the culmination of a colorful exchange captured on camera by local station WISN 12. According to the store manager, Biden later whispered that he was just kidding. He also said after the run-in that Biden was "very nice."
Earlier this year, the vice president made another unforgettable open-mic gaffe when he told President Obama that the passage of health care reform was "a big fucking deal" -- on live television.
WATCH: Biden Calls Ice Cream Store Manager A 'Smartass'