Moore plays a Columbia professor diagnosed with early onset Alzheimer's disease in "Still Alice," which is based on Lisa Genova's 2007 novel by the same name. Moore defeated Rosamund Pike, Reese Witherspoon, Felicity Jones and Jennifer Aniston for the honor. Moore was also nominated in the Musical or Comedy category for Best Actress for her role in "Maps to the Stars," but lost to Amy Adams for "Big Eyes." The actress previously won a Golden Globe for Best Performance by an Actress in a Mini-Series or a Motion Picture Made for Television at the 2013 ceremony for "Game Change." (She was also part of the Best Ensemble Cast award, a special citation from the Hollywood Foreign Press Association, for Robert Altman's "Short Cuts" in 1994.) This is Moore's second Golden Globe award overall.
Last year, Cate Blanchett won Best Actress in a Motion Picture - Drama for "Blue Jasmine."