The last No. 1 seed standing will take on the lone Cinderella team still hanging around in one national semifinal. No 1 Louisville will face No. 9 Wichita State in Atlanta, Ga. on Saturday.
The top overall seed in the tournament, the Cardinals steamrolled through their first two games by a combined margin of 57 points. After defeating No. 12 Oregon by eight in the Sweet 16, Louisville blew out Duke in the Midwest Regional Final.
After eliminating No. 8 Pittsburgh, the Shockers upset No. 1 Gonzaga in the third round and then No. 2 Ohio State in the Elite Eight to reach the Final Four for the second time in school history. Wichita State advanced to the Final Four in 1965 and was eliminated by UCLA.
''It's been a while, so to be able to go to the Final Four and represent all of us and try to win a championship, who knows?'' Wichita State coach Gregg Marshall said the win over Ohio State, via the Associated Press. ''We've had a lot of people support us along the way in Wichita and at the university and in our community. They're the best fans in the world.''
Take a look at these capsule glances at the teams' 2012-2013 seasons and let us know who you predict will reach the national championship game.
Regular Season Record: 27-5
Conference Record: 14-4 (Big East)
Conference Tournament Results: Won Big East championship vs. Syracuse
Top Player: Russ Smith (Guard)
Top 25 Wins: Missouri (#13), Marquette (#25), Syracuse (#12), Notre Dame (#24)
Worst Losses: Villanova (73-64)
RPI Ranking: 3
Regular Season Record: 26-8
Conference Record: 12-6 (Missouri Valley)
Conference Tournament Results: Lost to Creighton in MVC Title Game
Top Player: Cleanthony Early (Forward)
Top 25 Wins: Creighton (#12)
Worst Losses: Indiana State (68-55), Southern Illinois (64-62)
RPI Ranking: 37