The 30-second segment repeats the debunked claim that Democrat Michelle Nunn gave money to terrorists, and then goes on the criticize her for supporting "amnesty" at a time when "some experts say our border breakdown could provide an entry for groups like ISIS."
"Amnesty" is tea party shorthand for the comprehensive immigration reform bill that passed the Senate, largely thanks to the efforts of Republican Sens. John McCain (Ariz.), Marco Rubio (Fla.), Jeff Flake (Ariz.) and Lindsey Graham (S.C.).
The Democratic Senatorial Campaign Committee is taking advantage of that fact by doing it's own version of the Perdue ad, inserting the names and pictures of McCain and Rubio right after the narrator says "Michelle Nunn" and before it says "is for amnesty." (Watch it above.)
It leaves the rest of the ad as it was, making the point that anything the piece is saying about Nunn might as well be aimed at former and current GOP presidential contenders.
McCain himself did not seem too upset by the spot when HuffPost asked him about it, although he suggested it gets the problem exactly backwards.
McCain said that America's borders could be vulnerable to infiltration by terrorists (although intelligence officials say it's not a problem now.)
"It is a problem, and we'll have to assess the magnitude of it," McCain said. "It's also a problem the fact that they don't need a visa if they're European and can get on an airplane and come here."
But the immigration bill is not doing anything to encourage terrorists from the Islamic State, he said.
"No, not the bill itself," McCain said, noting that the reform measure would instead tighten the border.
"The bill actually calls for $8 billion to be spent on border security," McCain said.
Nevertheless, scare ads are becoming something of a theme as the campaign season heats up, and Perdue is hardly alone.
Watch the original ad below.
Michael McAuliff covers Congress and politics for The Huffington Post. Talk to him on Facebook.