In this clip from the special "Soul-to-Soul" episode of "Super Soul Sunday," Oprah asks a variety of spiritual thought leaders what they know for sure.
Oprah Winfrey: What do you know for sure?
Iyanla Vanzant: That God loves me. And I didn't do anything wrong.
Debbie Ford: That God never gives us more than we can handle. And that everything that comes our way is coming our way so that we can grow and evolve. And if we look at it that way -- if we're willing to open our hearts and see where we're shut down, where we're trying to resist life -- then we have a great opportunity to step into who we always wanted to be.
DeVon Franklin: That God is real. And that faith works.
Cheryl Strayed: That we're good at our core. And that love is really the only thing that matters. I know that sounds trite, but love is the center of everything. I think that love is the way. It is the thing that has delivered me to the best places even though sometimes it's brought me to the hardest places. We can all survive. We can all bear what we think we can't bear. And I learned that in all the things that I've experienced in my life.
Deepak Chopra: Nothing. How can you be sure?... Ten years from now you realize that what you knew then is not what you know now. That's the nature of the universe. What you see out there is the visible universe out there -- with its 175 billion galaxies, billions of stars, trillions of planets -- is 0.01 percent of what exists out there. So there's the known, there's the unknown, and there's the unknowable. In principle, unknowable. So if that doesn't make you feel humble, I don't know what will.
Llewellyn Vaughan-Lee: That everything belongs to God... And we are part of it.
Tune in to "Super Soul Sunday" on OWN, Sundays at 11 a.m. ET.