It Takes Two: Television's Most Classic Female Duos (SLIDESHOW)

A lot can be said of the bond between any female and her best friend... her BFF, her gal pal. And while there’s a flowery quote set against an equally flowery background for every such sentiment under the sun, this isn’t that kind of celebration.

Inspired by the eponymous leading ladies of Rizzoli & Isles, in concert with their imminent return to TV, we saw fit to take a look back at some of the most memorable female duos of the small screen.

Whether they're a bit more animated, genealogically relative, or even dubiously grounded in “reality,” all no doubt made it on here doing it their way. Sure, we may have taken some liberties with the rules—making room for dynamic dames that, while not strictly a pair, are too legit to omit—but, we like to think that when it comes to these fab femmes, the more the merrier.

Care to nominate a pair of pals that didn’t make our list? Let us know your favorites in the comments, and don’t forget to catch the season premiere of Rizzoli & Isles, Tuesday, June 5, at 9/8c.

Classic Female Duos on Television