One expert said Saturday's temblor was an aftershock of the devastating 2011 earthquake.
The quake, which had a preliminary magnitude of 7.1, shook buildings but no tsunami warning was issued.
More than 600 people were injured during the magnitude 6.2 quake, which sent people fleeing their homes in the darkness.
The quake was the strongest to hit the state since 1916. No injuries or damage were immediately reported.
The quake killed at least two people and sent thousands fleeing into the streets of Mexico City.
“We’re just having a bit of an earthquake here Ryan, quite a decent shake here,” the prime minister said during the live exchange.
The quake knocked out power to some homes and brought the light rail system to a halt.
The earthquake struck Elazig in the eastern part of the country with a preliminary magnitude of 6.8.
Some are concerned about tourism dropping to the island, much like it did after Hurricane Maria in 2017.
More than 3 million Puerto Ricans are without power and thousands are sleeping outdoors after earthquakes toppled homes.