A Miami speech is set for Friday to announce changes to the relaxation of tourism and trade rules.
"Fidel fears many things, and when you fear so much, you cannot love at the same time."
Among the passengers on the 150-seat Airbus A320 will be U.S. Transportation Secretary Anthony Foxx, JetBlue Chief Executive Officer Robin Hayes, news reporters and photographers.
It was rare to see an American flag in Cuba before the 2014 thaw in relations, but that appears to be changing.
As doors open to the island nation, conservation efforts are underway.
This is the Cuba we've been dreaming of.
Air travel and sending mail are just two things that have gotten easier since Obama and Castro agreed to resume diplomatic relations.
The deal comes on the one-year anniversary of the Cold War foes' decision to normalize relations.
