The Yankees slugger is now a homer short of matching Roger Maris' American League record.
The Monument Park marker appears alongside those dedicated to baseball greats Babe Ruth and Derek Jeter.
These popular names from 1919 are due for a comeback.
A few viewers celebrated that they knew something the record-breaking champ didn't.
Shohei Ohtani's three-run blast traveled nearly 400 feet.
"Battle of The Sexes," which hits theaters on Friday, recounts the match between Billie Jean King and Bobby Riggs in 1973. King defeated Riggs, but that wasn't the only time a woman won over a man in sports.
Sheen was the owner of the Bambino's 1927 World Series ring.