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An awkwardly insecure girl from the tenements of New York is forced, by societal conditions and a lack of viable options, into marriage to her boss; motherhood; and such continued repression that she finally takes matters into her own hands--mighty pretty hands, all the men tell her--and brutally murders her husband.
Going all the way back to Homer's Odyssey, some of our finest stories take place on voyages or quests of some kind, where our hero (or heroine) not only experiences new sights and adventures, but also some transformation in thinking, circumstance, or attitude as a result. The road movie is the cinematic equivalent.