From Prince to Muhammad Ali, there were some heartbreaking losses this year.
He told Oprah it was all about creating something more powerful than love.
"Out of despair, one creates. What else can one do?"
Wiesel, who spent his life exposing the horrors of intolerance, would not be impressed.
"He raised his voice, not just against anti-Semitism, but against hatred, bigotry and intolerance in all its forms."
The Nobel Committee called him a "messenger to mankind."