"There isn’t a big change I would make," MacFarlane said of 2010's "Quagmire's Dad," which GLAAD once deemed "incredibly offensive to transgender people."
“Think of the vaccine as a large ethnic bouncer, and COVID as the drunk, entitled white kid yelling ‘Do you know who my father is?’” Peter Griffin's doctor suggests.
The animated short ends with a lighthearted dig at Gal Gadot's "Imagine" video from early in the pandemic.
“This marriage isn’t working anymore.” Seth MacFarlane griped about “Family Guy” airing on Fox over its association with Tucker Carlson spreading misinformation about COVID-19.
"This marriage isn't working anymore."
The multitalented star eased stay-at-home boredom on "The Tonight Show" -- for a few minutes anyway.
'80s sitcom fans will always remember his Willie Tanner, who adopted a furry and funny alien.
Cher, Bette Midler, Seth MacFarlane and Mia Farrow were among those to torch Trump.
Seth MacFarlane took a personal interest in the episode, which revolves around serial assaulter Glenn Quagmire.
MacFarlane's shows "Family Guy," "American Dad!" and "The Orville" have all been on the Fox network.