we-need-to-see-pharmas-failures-as-much-as-its-successes

Sometimes, as I'm talking to patients and their families, I realize that I have no idea what I'm talking about. Really.
When 75 percent of our medical costs are for chronic diseases that are largely due to poor lifestyle habits, where are the studies on prevention? On behavior? On effective patient-doctor or public health strategies?
At present, most drug company records are treated as proprietary secrets. As a public health measure, drug companies should be required to make public all of their internal documentation concerning any drugs that begin the FDA approval process.
2013-01-18-TEDplayvideo.jpgWhile I am the first to admit to having pursued past research in this mindset (perhaps too publicly), I know that I am not the last -- so much so that many readers within my field won't bat an eye when agreeing to have done this at some point in their medical careers.
2013-01-18-TEDplayvideo.jpgMost writers, including myself, present a preferred reality to their readers. It is only natural for a writer to selectively choose or cherry pick outcomes in order to portray a certain image.
2013-01-18-TEDplayvideo.jpgIt's the result of a fundamental misunderstanding of placebo effects and control groups -- a misunderstanding that, scientists are now arguing, invalidates any claims of effectiveness for almost all psychological interventions.
2013-01-18-TEDplayvideo.jpgWhat Ben Goldacre does not take into account is the many ways in which, like most other humans, even the most rational scientists operate outside the constraints of their rational analysis.
2013-01-18-TEDplayvideo.jpgAs the body of published literature fails to paint the entire picture, eventually the gap between reality and what we think is reality widens. The negative results are still pertinent for several reasons.
2013-04-05-goldacrepullDoctors need the results of clinical trials to make informed choices, with their patients, about which treatment to use. But the best currently available evidence estimates that half of all clinical trials, for the treatments we use today, have never been published.