While the CDC has yet to identify the source of the outbreak, many of those infected had eaten burgers or sandwiches with romaine lettuce at Wendy's before falling sick.
The fast-food chain Wendy’s says it is pulling lettuce from sandwiches in its restaurants in Michigan, Ohio and Pennsylvania after people eating them there reported falling ill.
Officials say the tainted lettuce from Salinas, California, has sent 72 people to the hospital.
The leafy produce isn't the only food item that should be on consumers' radar this Thanksgiving.
Any romaine lettuce from California's Salinas Valley should be thrown out, the agency warned.
The illnesses come as beaches across the state and country battle elevated levels of bacteria, including E. coli.
The exact source of the bacteria is still under investigation, but all four children reported having contact with animals at the fair.
The recall involves over 4,600 cases of Pillsbury Best 5 lb. Bread Flour ― each of which contains eight bags.
Here's why your salad seems more susceptible to E. coli outbreaks than other foods you buy.
Food inspections are in jeopardy, thanks to the government shutdown.