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This Is The Possible Cause Of Memory Decline In Hispanics

This Is The Possible Cause Of Memory Decline In Hispanics
VOXXI
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A new study consisting primarily of Hispanic participants suggests common infections –- even those not linked to symptoms of illness –- may increase an individual’s risk for memory decline.

According to the data released from the American Stroke Association, cognitive performance and decline could be predicted by the number of specific antibodies present in study participants.

“We were very interested in what were the risk factors for cognitive performance and decline,” Clinton Wright, M.D., M.S., the study’s lead researcher and scientific director of the Evelyn F. McKnight Brain Institute, said in a press release.

The investigation was a more in-depth evaluation of previous links indicating a history of certain infections had been linked to an increased risk for stroke and Alzheimer’s disease.

At the end of the study, which evaluated almost 600 participants primarily of Hispanic ethnicity, experts were able to link degree of cognitive decline to antibodies associated with common infections of Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes simplex viruses 1 and 2. Individuals who tested positive for these specific antibodies had worse cognitive performance, including memory, speed of mental processing, abstract thinking, planning and reasoning ability, compared to individuals without a evidence of previous infection.

Though a link was established between common infection and cognitive decline, experts did not find a reason for the association, speculating that perhaps immune response to infection could cause damage over time that has previously not been identified.

“It could be caused by an immune system response to the infections or the infection itself could result in clinical damage that we’re not aware of,” said Wright. “There is no evidence yet that treating these infections is beneficial. It would be great if treatment prevented these bad outcomes, but we’re very far away from having that type of evidence.”

Right now, experts suspect the damage caused by infectious processes is so gradual that treatment of specific illnesses may not make a difference. It is possible the damage is cumulative over decades, making it difficult to determine how relevant the findings may be for future medical advancements. Wright also indicated more research needs to be done on other portions of the population; with 70 percent of study participants being of Hispanic heritage, the findings cannot be considered indicative of the general population.

According to U.S. News and World Report, chronic inflammation–the type associated with an immune response–is often considered the underlying cause of many disease processes, including heart disease, diabetes and cancer.

“In recent years, we’ve come to accept that inflammation plays a role in many chronic diseases, but it’s about an imbalance—too many pro-inflammatory chemicals and not enough anti-inflammatory ones,” Moise Desvarieux, an inflammation researcher at Columbia University’s Mailman School of Public Health, told the news outlet.

The trick is to catch inflammation as it is starting, indicate experts, rather than allowing it to become a chronic issue. Chronic inflammation can set off the body’s stress systems which then start an unhealthy chain reaction all their own–like the release of the stress hormone cortisol. Chronic exposure to this stress system can hurt the body rather than help it, a fact that supports the assumption common infection stress is cumulative.

Originally published on VOXXI as Infections might be to blame for memory decline in Hispanics

Before You Go

8 Easy Ways to Improve Your Memory
(01 of08)
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Ready for a pop quiz? Before reading any further, focus on the words to the left for one minute, then read (or reread) another article. When you're done, write down as many of the words as you can remember and return to this page to count up your total.Find out what your score means... (credit:Lisa Greene)
(02 of08)
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How'd you do? Recalling five or more of the words means your baseline short-term memory is in good shape. But if you came up with fewer, don't panic. maybe you were distracted by a text message, or maybe something else on the page caught your attention while you were reading the list (research shows that simply being unfocused can make it nearly impossible to add new information to your memory bank). Or maybe you just need to incorporate some brain training, which can activate and strengthen neural connections over time, allowing you to call up stored information faster.Gary Small, MD, director of the UCLA Longevity Center, who designed our test and uses a similar one to help diagnose memory problems in his patients, believes that certain behavioral techniques can help you stay sharper, longer. If you're perpetually misplacing your keys and forgetting to pick up milk at the grocery store, use these tactics to boost your memory today--and help prevent its decline down the road. (credit:Adam Voorhes)
Connect with Friends(03 of08)
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After tracking the social behaviors of more than 700 people over 15 years, Australian researchers found that those who maintained more close friendships scored better on memory tests (recalling symbols, pictures, and words). Being in regular contact with friends can keep you on your toes by engaging the problem-solving regions of your brain (as when you debate your latest book club pick or help a friend through a crisis). "It's important to be socially connected from a young age so that the lifestyle patterns you develop become ingrained," says Peter Snyder, PhD, chief research officer of the Lifespan Hospital System in Rhode Island. "We've found that when people prioritize these relationships, they also protect their brain function." (credit:Thinkstock)
Choose Stimulating New Hobbies(04 of08)
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As long as it interests and challenges you, the particular pastime doesn't matter -- it could be reading books in a genre you usually avoid, learning to play an instrument, or taking a new exercise class. A study by researchers at the Columbia University College of Physicians and Surgeons found that people with more than six intellectual, physical, or social leisure activities were 38 percent less likely to develop dementia -- and with each additional hobby, their risk decreased by another 8 percent. The fresh neural connections established as you take in new information can help build up what's called cognitive reserve--the brain's ability to resist memory loss. And the sooner you find new passions, the better: A 2012 study conducted at the University of California, Berkeley, found that people who performed more mentally stimulating activities throughout their lives had lower levels of a certain destructive protein associated with Alzheimer's. (credit:Thinkstock)
Go to Your Happy Place(05 of08)
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Many studies have shown that depression is linked to memory problems, but keeping your brain sharp requires more than just staving off the blues -- you need to actively practice positivity. A 2013 study in the journal Cognition and Emotion found that older adults who experienced positive emotions improved their memory by roughly 19 percent. "Positive moods are thought to trigger the release of the chemical dopamine in brain regions involved in memory, which may help improve recall," says study coauthor Ellen Peters, PhD, professor of psychology at The Ohio State University. If you want to reap the same benefits, try practicing meditation -- one study found that the proven stress buster can help increase dopamine levels. (credit:Thinkstock)
Brush Up on Your High School Spanish, or French, or German(06 of08)
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A study from the Rotman Research Institute found that bilingual Alzheimer's patients began experiencing symptoms of the disease five years later than patients who spoke only one language. "When you think in two languages, your brain cells may be working twice as hard," explains Small. "And the more often you fire up those neurons, the stronger they get." But it's use it or lose it: "If these connections aren't reinforced regularly -- as in the case of a neglected foreign language you learned decades ago -- they fade," says Neal Barnard, MD, an adjunct associate professor at the George Washington University School of Medicine and Health Sciences. (credit:Thinkstock)
Use Your Imagination(07 of08)
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Picturing yourself completing a task can help ensure that you remember to get it done. Researchers at the University of Arizona recently conducted a study in which participants were asked to memorize lists of words describing personality traits; having subjects imagine themselves acting out the traits proved the most effective technique for boosting their ability to immediately recall the words. The findings suggest that this technique could work for everyday memory tasks, from remembering to return shoes at the mall (picture yourself at the cash register) to remembering to stop by the dry cleaner's on your way home from work (imagine walking out with your clothes). (credit:Thinkstock)
Challenge Yourself at Work(08 of08)
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Whether you do it by changing careers or simply taking on more responsibilities at the job you have, finding something that pushes you out of your comfort zone can help protect against memory-deteriorating diseases. One study published in Neurology reviewed the work histories of people with and without Alzheimer's and found that those who developed the disease had fewer mentally taxing assignments. Researchers believe that the mental stimulation of more demanding jobs can help shore up cognitive reserves and stave off dementia. Says Snyder, "Routinely challenging yourself with projects that require you to multitask and solve problems fortifies systems in the brain that are important for memory."Help Researchers Learn More About Memory LossOne of the best things you can do to help scientists find a cure for Alzheimer's disease is to join the Alzheimer's Prevention Initiative, a new registry where you can volunteer to participate in medical surveys and clinical trials. You don't have to suffer from dementia to help -- the more people (both healthy and sick) who join, the more researchers can learn about what's going on in the human brain. Sign up at Registry.EndAlzNow.org. (credit:Thinkstock)
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