Florida State University Uncovers Drugs That May Stop Zika

Even better news? One of them is already on the market.
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Scientists have pinpointed two drugs that may stop the spread of Zika virus in the body and prevent its transmission from mothers to newborns, according to a report published this week in the journal Nature Medicine.

Since Zika’s worldwide outbreak became an international emergency last year, there’s been a mad scramble for ways to control the disease. So researchers from Johns Hopkins and Florida State University began a search for already-existing drug compounds that could also be used to treat the virus. And they believe they’ve found them: One compound is already used in a drug called Nicolsamide to treat tapeworm. The other is being tested for treatment of liver diseases.

“It takes years if not decades to develop a new drug,” Hongjun Song, one of the report’s directors, said in a statement. “In this sort of global health emergency, we don’t have time. So instead of using new drugs, we chose to screen existing drugs. In this way, we hope to create a therapy much more quickly.”

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Since the first compound is already on the market, doctors could theoretically prescribe it to Zika patients today, Science Daily notes. But in reality, more tests are needed to see exactly how effective the drug is at treating Zika in humans and design specific treatment plans. This process could take years, Dr. Guo-li Ming, one of the article’s co-authors, said in a statement.

Zika is a mosquito-borne disease that, while having mild symptoms, can be risky for pregnant women because of its tendency to cause birth defects in newborns. It’s currently especially prevalent in South and Central America, though 70 countries and territories have reported evidence of the virus since 2007. There have been more than 2,500 cases reported in the U.S., according to the Centers for Disease Control and Prevention.

There is currently no specific treatment for Zika. Scientists have been hard at work on a vaccine for the disease, but they’ve pursued drug research with less urgency, as Time notes.

While these two newly-identified drugs may take years to become mainstream Zika treatments, they’re a promising look into what could be a Zika-free future.

Before You Go

Zika Virus In Brazil
(01 of08)
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In Oct. 2015, Brazil alerted the World Health Organization to a sharp increases of babies born with microcephaly, a birth defect in which babies' heads are abnormally small.

A 4-month-old baby born with microcephaly is held by his mother in front of their house in Olinda, near Recife, Brazil, February 11, 2016.
(credit:Nacho Doce / Reuters)
(02 of08)
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Health officials in Brazil suspected that the sharp rise in microcephaly was linked to the country's ongoing Zika virus outbreak -- a mild, mosquito-borne disease that is estimated to have infected as many as 1.5 million people in Brazil.

Physiotherapist Jeime Lara Leal exercises 19-day-old Sophia, who is Ianka Mikaelle Barbosa's second child and was born with microcephaly, at Pedro l Hospital in Campina Grande, Brazil February 18, 2016.
(credit:Ricardo Moraes / Reuters)
(03 of08)
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Brazilian health officials soon advised women to delay pregnancy if possible, to prevent microcephaly cases. While they say the link between the two conditions is clear, WHO and other authorities say more research needs to be done before confirming the connection.

Jackeline, 26, uses a green bottle to stimulate to her son Daniel who is 4-months old and born with microcephaly, inside of their house in Olinda, near Recife, Brazil, February 11, 2016.
(credit:Nacho Doce / Reuters)
(04 of08)
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The zika virus was first identified in Africa, spread to parts of Asia and then reached the Americas in 2014, researchers suspect. The Aedes mosquito carries the disease.

An aedes aegypti mosquito is seen inside a test tube as part of a research on preventing the spread of the Zika virus and other mosquito-borne diseases at a control and prevention center in Guadalupe, neighbouring Monterrey, Mexico, March 8, 2016.
(credit:Daniel Becerril / Reuters)
(05 of08)
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Researchers suspect that the Zika virus is also linked to the spike of a rare, autoimmune disease called Guillain-Barré syndrome that can result in temporary paralysis.

A lab technician analyses blood samples at the 'Sangue Bom' (Good Blood) clinic in Rio de Janeiro, Brazil, on January 25, 2016.
(credit:VANDERLEI ALMEIDA via Getty Images)
(06 of08)
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There is no cure or vaccine for Zika virus. The most reliable way to prevent transmission is to destroy the mosquitos that carry it.

Joseph Blackman, a Miami-Dade County mosquito control inspector, uses a sprayer filled with a pesticide in an attempt to kill mosquitos that are carrying the Zika virus on October 14, 2016 in Miami, Florida.
(credit:Joe Raedle via Getty Images)
(07 of08)
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Zika virus is now endemic in dozens of countries and territories. The U.S. Centers for Disease Control and Prevention issued a travel warning to all Americans, and pregnant women in particular, to follow strict guidelines in preventing mosquito bites when traveling to these areas. Pregnant women were also advised to delay travel if possible, while women who want to become pregnant were advised to speak with their healthcare providers before traveling.

An employee of the Health Ministry sprays anti-mosquito fog in an attempt to control dengue fever at a neighborhood in Jakarta, Indonesia. (Photo by Risa Krisadhi/Pacific Press/LightRocket via Getty Images)
(credit:Pacific Press via Getty Images)
(08 of08)
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Several research institutes and companies are now trying to figure out how to create a vaccine for Zika virus. However, it will be years before anyone develops a reliable vaccine, researchers predict.

A nurse from the FioCruz Foundation applies the dengue vaccine to social worker Ana Paula Rocha, 41, who volunteered for the vaccine tests.
(credit:NurPhoto via Getty Images)

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