The Connection Between Autism And Epilepsy

The Connection Between Autism And Epilepsy
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By: Dr. Megdad Zaatreh, medical director, Comprehensive Epilepsy Center at CentraState Medical Center
Published: 05/29/2014 06:59 PM EDT on LiveScience

Dr. Megdad Zaatreh is a board-certified neurologist with expertise in epilepsy who serves as medical director of the Comprehensive Epilepsy Center at CentraState Medical Center in Freehold, N.J. Zaatreh has published several research articles in peer-reviewed medical journals, including the New England Journal of Medicine, Neurology and Epilepsia. He contributed this article to Live Science's Expert Voices: Op-Ed & Insights.

Studies estimate that nearly one-third of people with autism spectrum disorder also have epilepsy. However, until recently, there was only limited clinical research on the connection between these two neurological conditions.

Epilepsy is a brain disorder marked by recurring seizures or convulsions. Autism is a neurobehavioral disease that includes impairment in social interaction and language development, which often includes rigid, systematic, repetitive behaviors. Both conditions can affect individuals with varying degrees of severity. Now, research has found that adults with epilepsy are more likely to show signs of autism and Asperger syndrome.

Until recently, in many cases, adults with epilepsy may not have been properly diagnosed or treated for autism symptoms. The connection between the two conditions was the result of a study that showed epileptic seizures short-circuit the neurological function that affects socialization in the brain, which are the same traits seen in autism. These characteristics include the impairment of normal social interaction (eye contact, conversation, enjoying the act of sharing with someone else) and tightly regimented or repetitive cycles of behavior.

Socialization challenges for people with epilepsy

Before those studies, the issues with socialization and behavioral management for some people with epilepsy were underdiagnosed — and research had not uncovered any underlying theory to explain them. Without diagnosis, there is no treatment plan.

However, the new evidence explains that the misfiring of the brain during a seizure may explain the cause of the autism conditions. Not surprisingly, the more frequent the epileptic seizures, the more severely impacted the patient's socialization issues may be.

These new findings could mean that adults with epilepsy can now benefit from the wide range of autism treatment services available to help address the long-standing socialization issues many patients with epilepsy have experienced throughout their lives. This offers the possibility of significantly improving epileptics' overall quality of life. Up to this point, there have been few services to address those needs.

(If your child is diagnosed with autism , consult with a pediatric neurologist to screen for epilepsy as well.)

Recognizing symptoms of epilepsy in infants

The highest incidence of epilepsy occurs during the first year of life, when many new parents overlook or misinterpret physical symptoms. Each year, 150,000 children and adolescents in the United States will have a newly occurring single seizure, and 30,000 will be diagnosed with epilepsy after subsequent seizures occur. During early childhood development, infants often exhibit a variety of erratic physical movements and mannerisms that may not cause immediate concern. But babies or children presenting any of these symptoms should be seen by a doctor immediately:

  • A prolonged staring spell
  • Uncontrollable jerking movements of the arms and legs
  • Lack of response or awareness to verbal stimulation
  • Shaking, loss of balance or smacking of the lips

Specialty care is available for children with epilepsy

If you suspect your child may have experienced a seizure, contact your pediatrician immediately for an evaluation. While the seizure is frightening for parents and caregivers, it is important to observe and record the duration of the episode as well as the symptoms the child exhibited before and after the episode. Share this valuable information with your doctor.

Keep in mind that some hospitals offer specialized epilepsy treatment programs exclusively for pediatric patients.

Follow all of the Expert Voices issues and debates — and become part of the discussion — on Facebook, Twitter and Google +. The views expressed are those of the author and do not necessarily reflect the views of the publisher. This version of the article was originally published on Live Science.

Copyright 2014 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. ]]>

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Before You Go

Facts About Autism
1 In 68 Children Are Identified As Having Autism Spectrum Disorder (01 of09)
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According to the most recent Centers for Disease Control and Prevention estimates, 1 in 68 children in the United States has an autism spectrum disorder, based on health and education records. That figure represents a significant increase from previous prevalence estimates, released in 2012, which estimated that 1 in 88 have an ASD. (credit:Gettystock)
Boys Are More Likely To Have Autism Than Girls(02 of09)
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Autism is roughly five times more common in boys than girls, according to CDC estimates. One in 42 boys have been identified with autism, compared to 1 in 189 girls.Children born to older parents are also more likely to have an ASD. (credit:Shutterstock)
The Symptoms Of An ASD Can Present Themselves In Infancy(03 of09)
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According to the NIH, early indicators include: No babbling or pointing by age 1, no single words by 16 months, poor eye contact, little to no smiling or other social responses and more. (Click here for more information from NIH.)The CDC says, "Health care providers will often use a questionnaire or other screening instrument to gather information about a child’s development and behavior. Some screening instruments rely solely on parent observations, while others rely on a combination of parent and doctor observations. If screening instruments indicate the possibility of an ASD, a more comprehensive evaluation is usually indicated.” (credit:Shutterstock)
Scientists Are Not Certain What Causes Autism(04 of09)
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According to the Child Mind Institute both genetic and environmental factors could contribute. (credit:Getty Images)
There Is No Cure For Autism, But There Are Ways To Treat It(05 of09)
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Autism is treated with therapy, education plans and medication. Doctors and scientists say that early identification and intervention for children with an ASD can help them thrive in academically and socially in the future.There are still studies being done to find better treatments and perhaps one day, even a cure. A paper in Cell, a scientific journal, discussed a study with more insight into what could cure autism. The study found that feeding rats with similar symptoms to autism a gut bacteria called B. fragilis lead to an improvement in their behavior. "They became less anxious, communicated more with other mice, and showed less repetitive behavior,” according to the Atlantic. (credit:Shutterstock)
Research Shows That There Is No Link Between The Onset Of Autism And Vaccinations (06 of09)
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Even when multiple vaccines are given to a child on the same day, they are still not at risk of developing autism. (credit:Shutterstock)
If A Child Has An ASD, Their Sibling Has A 2–18 Percent Chance Of Also Being Affected (07 of09)
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Studies have also shown that if a child with an ASD has an identical twin, the other will be affected anywhere from 36-95 percent of the time. (credit:Shutterstock)
20 To 30 Percent Of Children With An ASD Develop Epilepsy(08 of09)
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Children whose language skills regress before they turn 3 have been found to have a higher risk of developing epilepsy. (credit:Alamy)
Infants And Young Children Should Be Screened For Developmental Delays At Periodic Intervals(09 of09)
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The CDC recommends children be screened when the are 9, 18 and 24-30 months. (credit:Shutterstock)

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