More Than 1 In 4 Medical Students Are Depressed, Analysis Finds

A high-pressure environment and the stigma attached to mental illness aren't helping.
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A new survey estimates that 27 percent of medical students are depressed.

F.I., 31, is in her final year at the University of California, San Diego School of Medicine. She’s studying to be an emergency department doctor, and come March 17, or “Match Day,” she and thousands of other medical students across America will find out if they got matched to a hospital residency program after graduation.

F.I. has something else in common with many of her medical school colleagues: She’s struggled with depression and suicidal thoughts. These are issues she’s dealt with since she was 10 years old, but F.I., who asked that we use her initials due to concerns about mental health stigma in her field, said her symptoms got worse when she was applying to medical school.

When F.I. got into a top-20 medical school, she thought her problems were over. But soon, the relentless competition and insecurities about not being smart or prepared enough re-triggered her old depression symptoms.

“I still remember the day I got the acceptance letter,” said F.I. “I was really shocked and I was incredibly happy, and I thought all those feelings of inadequacy would be gone.”

“But then after I started, they all returned, and it’s never-ending,” she continued. “Then you have to apply for residency, and it’s like the same thing all over again.”

F.I. isn’t alone in her struggle, and American medical students aren’t unique in their unusually high rates of depression and suicidal thoughts. A large-scale analysis of 195 studies involving over 120,000 students in 47 countries found that 27 percent of medical students experience depression or depression symptoms, with more than 1 in 10 reporting suicidal thoughts. To put that in perspective, this means that medical students are five times more likely than the general population to have depression.  

The study, published this month in the Journal of the American Medical Association, found that, on average, students experienced a 13 percent increase in depression symptoms when they started medical school. Students in both the beginning and later years of their programs were equally at risk, and medical residents, too, face comparably high rates of depression. 

How Medical School Raises The Risk For Depression

The study doesn’t delve into why medical students would have elevated depression rates and suicidal ideation. But there are a few possibilities, says Dr. Douglas Mata, a pathology resident at Brigham and Women’s Hospital and clinical fellow at Harvard Medical School who was the study’s senior corresponding editor.

“There are times when she said, like, ‘Some things you say are stupid,’ or ‘You should have already known that' ... She just really thought I was bad, and she made sure I knew it.”

- F.I., student at the University of California, San Diego School of Medicine

Medical school is notorious for its long hours, demanding course loads, competitive atmosphere and high rates of stress and burnout. While it’s well-known that this pressure-cooker environment can take a toll on students’ mental health, new research suggests that depression among medical students may be even more widespread than is usually acknowledged.

Lack of sleep is a known risk factor for depression, and students’ chronic sleep deprivation from studying and working overnight shifts at hospitals could increase depression rates, Mata said. Plus, the amount of financial debt that students take on in order to graduate could make them feel mentally and emotionally trapped. Medical students who graduated with debt in 2014 owed an average of $180,000, according to the Association of American Medical Colleges.

“Sometimes people feel trapped by that, because in addition to not having enough money to do everyday things, if, God forbid, you decide that maybe you made the wrong decision and that medicine is not actually what you want to do, you’re pretty much locked in just for monetary reasons,” said Mata. “You really don’t have a choice of quitting and starting anew if you’ve gotten yourself into that much debt.”

F.I. is confident that she wants to become a doctor, but she does identify strongly with all the other risk factors Mata outlined. Her worst bouts of depression occurred during her pediatrics rotation, when she had to work a 30-hour shift every five days, and during a surgery rotation, when she felt her attending supervisor conveyed daily that she didn’t belong in the rotation, in the hospital or even in medical school.

“There are times when she said, like, ‘Some things you say are stupid,’ or ‘You should have already known that,’” F.I. recalled. “She just really thought I was bad, and she made sure I knew it.”

Finally, while she receives financial aid to go to school, the money doesn’t cover F.I.’s everyday expenses like groceries and bills. She is in debt, and to make extra money, she recently started driving for Uber and Lyft whenever her busy schedule allows.

What Schools Are Doing To Protect Their Students

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Ben Edwards/Getty Images
Some schools provide mental health services for students, but there are other important steps they can take, experts say.

To cope with the pressure on multiple fronts, F.I. took advantage of her school’s free counselors. She found help from professionals she liked and trusted, calling it “one of the best experiences” she’s ever had in her life. But when a friend and fellow medical school student committed suicide in 2015, she found herself fantasizing about death as a type of freedom or escape. That’s when F.I. realized she needed to start seeing a psychiatrist, who then went on to prescribe her antidepressant medication.

Too many students like F.I., as well as full-fledged doctors, are struggling with med school and hospital life. An estimated 300 to 400 doctors commit suicide every year, and the medical profession is scrambling to come to terms with how to change so it can protect physicians from this risk.

F.I. feels she is now getting the help she needs. While she still struggles with depression symptoms, she’s looking forward to Match Day and enjoys spending time with her patients. 

Some schools provide mental health services through their psychiatry departments and others offer free counseling for students, but these programs assume that students will seek help, and they may not be enough to address the structural features of medical school that increase depression. For instance, Mata’s meta-analysis found that only 16 percent of the students who screened positive for depression sought treatment.

Examples of institutional change, on the other hand, include Saint Louis University School of Medicine’s recent decision to adopt a pass/fail system and reduce class time by 10 percent, which resulted in improved academic performance and fewer students reporting symptoms of anxiety and depression.

While Mata says that it’s a good sign more medical schools are taking the mental health and well-being of their students seriously and offering services like free counseling, yoga or mindfulness meditation, institutions need to take a more structural approach to change.

“Both of these things put the onus on the student, and I don’t think get to the root causes of depression, which are more system-based issues,” he said. “There are a couple of big changes that can be made.”

The Culture Around Mental Health Needs To Change

There are certain deeply ingrained aspects of medicine culture that make it difficult to fix this problem, Dr. Stuart Slavin argues in an editorial also published in JAMA.

“If you meet criteria for major depressive disorder, you shouldn’t stay home, dig your heels in and try to tackle it on your own.”

- Dr. Douglas Mata

“The first is the belief by some that medicine is a demanding profession and, therefore, medical school should also be extremely rigorous and demanding. If students are not ‘strong’ enough to handle the stress, then they should probably seek another profession,” wrote Slavin, who is the associate dean for curriculum and a pediatrics professor at Saint Louis University School of Medicine. “A second aspect of medical culture is that mental problems ordinarily have not been taken as seriously as physical problems.”

Mental illness stigma is particularly rampant in the medical community, Slavin suggests, and likely prevents students from seeking help.

Mata hopes that his study and similar research serve as a wake-up call for both medical schools and medical students. Just as a person with an infection would go to a doctor for antibiotics, or a person with diabetes would take a pill or insulin, people with depression should seek medical treatment, he concluded.

“If you meet criteria for major depressive disorder, you shouldn’t stay home, dig your heels in and try to tackle it on your own,” Mata said. “You should go see somebody, because both medication and therapy are equally effective, and it’s not a sign of weakness for people to get treated for their illness. It’s an illness just like any other.”

If you or someone you know needs help, call 1-800-273-8255 for the National Suicide Prevention Lifeline. Outside of the U.S., please visit the International Association for Suicide Prevention for a database of resources.

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Before You Go

Bizarre Questions People Ask Doctors
'Why Don't We Get Goose Bumps On The Face?' (01 of07)
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We do get them on our cheeks, says Jessica Krant, MD, a board-certified dermatologist and assistant clinical professor at SUNY Downstate Medical Center. Goose bumps, or cutis anserine, occur where we have hair -- pretty much everywhere except for our palms and soles of feet, Krant says. She breaks down the process: Each hair follicle contains a microscopic muscle called arrectores pilorum that contracts in response to the sensation of cold, or the feelings of fear or excitement. The reason most of us, especially women, don't notice goose bumps on our face is because the peach fuzz there is usually fine and short, and our facial skin muscles are less robust than those in our arms and legs. Krant adds that if you find goose-pimply bumps on any part of your body that don't seem to be affected by fear or temperature, you might have keratosis pilaris, an eczema-like condition caused by inflamed follicles. (credit:Thinkstock)
'Does Being Overweight Mean You'll Get Pregnant Easily?' (02 of07)
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We don't see many images of fertility goddesses as skinny stick figures. And it's true that underweight women make a form of estrogen that can be too weak for successful conception, according to the American Society for Reproductive Medicine (ASRM). But while obese women often have an overabundance of estrogen, this can affect their cycle to the point that they stop ovulating. Excess weight can influence fertility in other ways, too: A 2007 Dutch study of more than 3,000 couples (without any known ovulation problems) found that women with a body mass index of 30 or higher had significantly lower probability of becoming pregnant, when compared with women with BMIs of between 21 and 29. This is why the ASRM stresses the importance of maintaining a healthy weight when trying to conceive. By the way, having full hips won't even provide an advantage during childbirth: "It's the front-to-back dimension that creates the tightest squeeze," discovered Nathanael Johnson while exploring the science and history of childbirth (among other biological processes) for his book All Natural. So an average-weight woman has the best chance of getting pregnant naturally and giving birth more easily. (credit:Thinkstock)
'Why Don't People Who Take Nitroglycerin For Their Heart Blow Themselves Up?' (03 of07)
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This query usually exposes a childhood fascination with Road Runner cartoons, says Billy Goldberg, MD, a New York emergency room physician and the co-author (with Mark Leyner) of twobooks about health trivia ("the stuff everyone wants to know, but that doctors aren't taught in medical school," Goldberg says). For those who've forgotten: Wile E. Coyote would blow himself up with explosive nitroglycerin -- the same substance used in heart medication. In the commonly prescribed pill form, nitroglycerin helps increase blood flow to oxygen-deprived areas of the heart by dilating blood vessels. The medicinal dose of nitroglycerin in heart medication is infinitesimal compared with the amount in a stick of dynamite, explains Goldberg in Why Do Men Fall Asleep After Sex?. It's also highly diluted for safe handling. (credit:Thinkstock)
'Can Sunshine Trigger A Sneezing Fit?'(04 of07)
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Goldberg says this is one of his favorite questions -- mostly because he assumed it was too ridiculous to be true. While writing Why Do Men Have Nipples?, he and Leyner pored over medical textbooks and studies to find out that some people have a strange reaction to blazing sunlight that causes them to sneeze uncontrollably. This is due to something called the photic sneeze reflex -- also known as autosomal dominant compelling helio-ophthalmic outburst, or ACHOO. A 2005 study of six Spanish families showed that there are usually two to three "achoo"s per episode of ACHOO. This reflex is relatively under-studied and not completely understood, says Goldberg, but it is thought to have something to do with an accidental crossing of nerve signals. (credit:Thinkstock)
'Why Does It Feel So Hot Out When It's 90 Degrees If Our Bodies Are 98.6?' (05 of07)
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This question comes up all the time, says Goldberg (most likely during the sweltering East Coast summers). The answer is found in the human body's way of regulating temperature. We're constantly producing heat as we burn calories and exert energy, says Goldberg, and the heat needs to escape. He explains that it's easier to release pent-up heat when the temperatures outside are moderate or cool. When the temps soar, the body increases blood flow to the skin to help the heat escape through sweat. The hotter it gets, the more sweat and energy the body needs to exert, and the harder it ends up working. As a result, you feel like you're burning up. (credit:Thinkstock)
'If You're Stranded On A Desert Island Should You Drink Ocean Water Or, Um, Your Own 'Water'?' (06 of07)
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This is definitely one of the more far-fetched questions Goldberg has been asked in his 20-plus years as an emergency room doctor and assistant professor of emergency medicine at New York University. But the answer underscores the importance of staying hydrated at all times. Our drink of choice would have been seawater. But Goldberg informs us that we have it wrong: Seawater is three times as concentrated as human blood, and to process it, the body would need to excrete the excess salt through the kidneys as urine. As your body worked to flush out the salt, you'd lose precious fluids and become even more dehydrated. Before long, your muscles would atrophy, your heart would pound out of rhythm, and you'd eventually die of dehydration. He says it's probably safer to drink urine than seawater, but you'll probably be too dehydrated to make enough to quench your thirst. (credit:Thinkstock)
'Can Pins And Needles In Your Feet Cause You To Become Paralyzed?'(07 of07)
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Goldberg says he's seen many people end up in the ER because they've failed to respond to that weird prickly feeling, perhaps because they've been knocked out by alcohol, sleeping pills or a punch in the face. He explains that when you've been kneeling for too long (or doing something else that puts pressure on your leg), the arteries in that area can become compressed, preventing them from providing tissues and nerves with oxygen and glucose. This also blocks nerve pathways, causing some nerves to stop firing and others to go off like a 4th of July fireworks finale. When the brain receives these signals, it interprets them as that uncomfortable sensation of pins and needles. Prolonged pressure on the arteries can indeed lead to temporary or even permanent nerve damage, so it's important to respond to the feeling as soon as you notice it. (credit:Thinkstock)

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